Constituents of Sideritis syriaca. ssp syriaca (Lamiaceae) and their antioxidant activity

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Title

Constituents of Sideritis syriaca. ssp syriaca (Lamiaceae) and their antioxidant activity

Creator

Kokkalou, E.

Gabrieli, C.

Zervou, M.

Termentzi, A.

Description

The aerial parts of Sideritis syriaca ssp. syriaca (Lamiaceae) were extracted, after defatting, with diethyl ether, ethyl acetate and n-butanol. The antioxidant activities of the extracts were evaluated through in vitro model systems, such as 1,1-diphenyl-2-picryl hydrazyl (DPPH) and Co(II) EDTA-induced luminol chemiluminescence. In both model systems the ethyl acetate extract was the most effective. Phytochemical analysis of ethyl acetate extract showed the presence of two new isomeric compounds (II and V), identified as 1-rhamnosyl, 1-coumaroyl, dihydrocaffeoyl, protocatechuic tetraester of quinic acid, as well as chlorogenic acid (2), apigenin 7-O-glucoside (3), apigenin (4), 4'-O-methylisoscutellarein 7-Cr-[6'''-O-acetyl-beta-D-allopyranosyl-(1 -> 2)-beta-D-glucopyranoside (5), isoscutellarein 7-O-[6"'-O-acetyl-beta-D-allopyranosyl-(1 -> 2)-beta-D-glucopyranoside] (6), 4'-O-methylisoscutellarein 7-O[beta-D-allopyranosyl-(1 -> 2)-beta-D-glucopyranoside] (7) and 4'-O-methylisoscutellarein 7-O-[beta-D-allopyranosyl-(1 -> 2)-6 ''-O-acetyl-beta-D-glucopyranoside] (8). The above compounds were identified by spectroscopic methods.

Type

Article