Extraintestinal Manifestations of Inflammatory Bowel Disease. Hematological, Vascular and Coagulation, Renal, Pulmonary

 
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2007 (EN)

Extraintestinal Manifestations of Inflammatory Bowel Disease. Hematological, Vascular and Coagulation, Renal, Pulmonary (EN)

Ilias, A.
Maris, Th.

Extraintestinal manifestations of inflammatory bowel disease (IBD) have been joined with almost every system. Over 100 extraintestinal manifestations have been described. Many of these problems are common in Crohn’s disease and ulcerative colitis but they are more prevalent in Crohn’s disease than in ulcerative colitis. The incidence of extraintestinal manifestations has been estimated from 20% to 40%. It has been shown that if a patient presents with one manifestation, the possibility to develop one more is greater than that expected by chance. This phenomenon suggests a common pathophysiological mechanism of all these conditions. The exact pathophysiological mechanism of extraintestinal manifestations is not known, but generally they could be chronic immune reactions to circulating autoantibodies. For educational reasons, extraintestinal manifestations may be divided into two groups, manifestations associated with active bowel disease (either small or large) and problems that occur independently of the presence of inflammation. (EN)

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English

2007-04-05


Hellenic Society of Gastroenterology (EN)

1792-7463
1108-7471
Annals of Gastroenterology; Volume 19, No 2 (2006) (EN)




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