1. Home page
  2. Search

Melting of genomic DNA: Predictive modeling by nonlinear lattice dynamics

This item is provided by the institution :
National Hellenic Research Foundation (NHRF)   

Repository :
Helios - Repository of the National Hellenic Research Foundation (NHRF)  | repositories EKT   

see the original item page
in the repository's web site and access all digital files if the item*



Melting of genomic DNA: Predictive modeling by nonlinear lattice dynamics
Θεοδωρακόπουλος, Νίκος
Άρθρο σε επιστημονικό περιοδικό
2010-08-06
The melting behavior of long, heterogeneous DNA chains is examined within the framework of the nonlinear lattice dynamics based Peyrard-Bishop-Dauxois (PBD) model. Data for the pBR322 plasmid and the complete T7 phage have been used to obtain model fits and determine parameter dependence on salt content. Melting curves predicted for the complete fd phage and the Y1 and Y2 fragments of the phi X174 phage without any adjustable parameters are in good agreement with experiment. The calculated probabilities for single base-pair opening are consistent with values obtained from imino proton exchange experiments.
College Pk
Φυσική (EL)
Physics (EN)
Physics, Fluids & Plasmas
Physics, Mathematical
English
American Physical Society
Physical Review E
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.el
National Hellenic Research Foundation (NHRF)
Helios - Repository of the National Hellenic Research Foundation (NHRF)



*Institutions are responsible for keeping their URLs functional (digital file, item page in repository site)